VoicedByMe ($30 once, Windows and Mac)
Natural AI voices that run on your computer: 70 ready-made voices, or your own from twenty seconds of talking. Select text in any app and press CtrlAltR, open PDF, EPUB and Word files, save audio, and make audiobooks with chapters. It reads English, Spanish, German, French, Portuguese, Italian, Japanese and Russian, and needs a recent graphics card or Apple silicon for fast reading.
Panopreter Basic (free, Windows)
A simpler free reader that reads text and documents and saves them as WAV or MP3. Like Balabolka, it uses the voices installed in Windows.
TextAloud 4 ($34.95 once, Windows)
A long-running reader from NextUp that saves text as MP3 and other formats, with a 30-day money-back guarantee. More natural voices are sold separately.
NaturalReader desktop (from $99.50 once)
The desktop version of NaturalReader includes two natural voices and MP3 saving in its Personal edition. Extra voices are $39.50 each. More in our NaturalReader comparison.
Piper (free, open source)
A neural voice engine with natural voices in dozens of languages that runs on an ordinary processor. It's a command-line tool; a few small community apps put a window around it.
On a Mac: Spoken Content and the say command (free)
Download a Premium voice in System Settings → Accessibility → Spoken Content and press OptionEsc to hear any selected text. To save audio, the Terminal command say -f text.txt -o speech.aiff writes a file.